problem? purpose

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flounder
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Zohydro - I don't see the problem, but then I don't see the purpose.

http://today.msnbc.msn.com/id/45791556/ns/today-today_health/t/new-powerful-painkiller-has-abuse-experts-worried/?ocid=ansmsnbc11

 

celticgreenman
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No APAP

Besides a chance to patent a drug (to make revenue), I think the main reason is to get a hydrocodone medicine without the APAP in it. With the problems that APAP is producing, many intities are trying to limit it.

So, it sounds like they are trying to produce a controlled release, hydrocodone only, tablet.

Just yet another option for the pain management physicians.

cgm

wally
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I see this subject has

I see this subject has already been addressed. I know the main two reasons for the new formula are

First and formost: REVENUE. Wink

And second: elimination of the APAP.

I just hope I still have the option of getting my old hrdro tens. My insurance pays for them.

The media isn't helping matters at all. They have been spewing out scare tactics every since news of the new formula came out and getting everone in an uproar.

nhm
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Hey, anyone recall someone

Hey, anyone recall someone here at pharmer mentioning that their dr got them in a CR hydro study a while back?

gtrplayer
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Who knows

While I do not doubt that someone claimed their doctor got them in a Hydrocodone CR study, I do not recall anyone ever posting a verifiable image of a controlled release hydrocodone product. For as long as I have been here, it seems like there has always been mentions of a controlled release hydrocodone product, most notably, the link to Vicodin CR (I think, without looking, it was a patch).

Either way, I very highly doubt that anyone here has actually been on a controlled release hydrocodone product, despite their claims. If you have been on "Hydrocodone CR", please, upload an image of the tablet, patch, etc,, with descriptive markings facing the camera so we can verify the Manufacturer.

Regards,

Gtr

 

celticgreenman
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Studies for Hydrocodone ER

Melinda,

The following is a list of some of the studies being done or have been done for hydrocodone ER. It is by no means a complete list. It does not include possible studies being done by academic institutions. There is no guarantee that these studies have actually gotten off the ground, are currently in progress, are enrolling subjects, or anything else.

There are studies out there, maybe. If you are interested in being a subject, the best place to start is with your pain management physician, as he/she may have received flyers from institutions/pharmaceutical companies who are looking for subjects. Another place to look would be NIH (National Institutes of Health) in Washington DC.

Usually, you have to luck into being a subject; be in the right place and the right time. Sometimes, NIH will compile lists of patients willing to be subjects, and give them a call if a study comes up, same with many academic institutions.

.
List of government trials using Vicodin. You have to read the studies, because some are with CR, while others are with the usual IR formulation. Also, some of these are enrolling, others are completed.
http://www.druglib.com/druginfo/vicodin/trials/

Study currently enrolling subjects (as of June 2011) for the study of the safety of hydrocodone ER in patients requiring long term opioid therapy.
http://clinicaltrials.gov/ct2/show/NCT01223365

Study for Vicodin CR after bunionectomy. This study is complete, but the researchers have not yet published their findings in any peer reviewed literature.
http://clinicaltrials.gov/ct2/show/NCT00402792

The following is a study by the pharmaceutical company, and I believe it is completed. It was for hydrocodone ER, it was one of the trial phases required by the FDA. It is for Zohydro, the medication that started this thread.
http://www.tm-partners.com/news/081711.html

.
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So, there are some studies out there, but since there are so few, it is really difficult to get to be a subject. You usually have to be in a large city, and again, in the right place and the right time. But, you can always look into it. Start with your pain management physician. Sometimes pharmacists will know of upcoming trials. If you are close to a medical school, you can contact their IRB (Institutional Review Board) to see if there are any studies being considered. And, of course, there is always the NIH. Oh, and maybe the FDA.

Good luck.

nhm
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Cgm,Hey, thanks for all the

Cgm,

Hey, thanks for all the info, you rock! But NO, SO NOT intersted in being a "subject" aka lab rat, lol, no thanks. No, I was just wondering if perhaps some one on here had reliable, real life experience and info to share; I thought Id read of a pharmer in a  CR hydrocodone research study.

I personally think its a good painkiller, too bad it only lasts about 3 hours in me it seems like. So I have to decide which 12 hours of the day to medicate, as I get 4p/d. So if this goes thru (has it indeed been brought to market, or are we in the wait and see phase?), sure, Id be interested.. Unfortunately I have a Dr. that isnt interested, aparently.... oh well, cant win them all, right?

Anyway, thanks for getting back to  me!

Melinda

celticgreenman
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Zohydro

Melinda,

It is not out yet. It is due for NDA submission in early 2012.

If you click on the last link in my previous post, it talks about its latest Phases III trials. The medicine is known as Zohydro.

cgm

nhm
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Im sorry, Im SO behind since

Im sorry, Im SO behind since I havnt been on (Pharmer)in so long; I will definately check those links out asap though!

Thanks, and take care,

Melinda

Benny Badback
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NHM-

You might also sign-up at clinicalconnection.com   There are literally 1,000s of studies and trials going on... You sign-up for whatever you want, fill out a Q/A and then they send you info re: trials in your area. Some are also paid spots, reimbursement of expenses, etc. etc.