New Opana & P.R.P. (STEM CELL) Injections

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thescirocco
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I went to talk to my new pain doctor, to see if I could get Opana IR, instead of the recently changed Opana ER.

He specializes in injections, standard injections, and now also PRP, which I had never heard of. Hearing about PRP gave rekindled any hope, of getting my shoulder back to normal, and I was totally sold.

PRP, Platelet-rich plasma, is where they take ~80cc's of your own blood, run it through a centrifuge, to separate the good platelets, they then inject this into the affected joint, and it uses your own stem cells to regenerate the bad joint.

http://en.wikipedia.org/wiki/Platelet-rich_plasma

Coby Bryant recently went to Germany to have this procedure done, with outrageous effects:

http://lakernation.com/2011/07/dr-raj-explains-kobe-bryants-prp-knee-procedure/

Yes, I think I have ADHD... Laughing

Anyway, getting back to the new Opana ER... As most of you know, Opana IR's are on back-order and most drugstorews do not have them. Opana's manufacturer has created a toll free phone number, 877.498.3869, to assist you in locating Opanas. I told the operator that the new Opana made me sick, and that's why the doctor switched me to the IR, instant relief. At the end, the operator asked me about my problems with the new Opana, and she said she'd relay that to her superiors. So calling this number, and reporting the new Opana problems, seems that it would be as effective as writing them. So if every disgruntled Opana user could call 877.498.3869 and include your name, number, and say yes, to allowing them to contacting you.  The operators were not successful in finding my meds, in a 20 mile circle, so I'll probably have to go back to Oxycodone, or Oxycontin, until the Opanas are made available again.

If you have problems with the new Opana, please call 877.498.3869...

Thanks!

Peter

 

 

celticgreenman
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PRP

As to the PRP, unfortunately, there is no confirmed research that it's effects are true.  The American Academy of Orthopedic Surgeons still considers it experimental.  The success stories are ancedotal;  a big time pro athlete gets the injections and does great.  (Who says the placebo effect doesn't work!)  But, there is no solid research proving that it actually works.  The research out there goes both ways.  Some says it works and some says that it is a total flop.   Unfortunately, the methodology used on most of the studies was pretty shaky, both sides.

 

So, research continues.  If you decide to have the procedure done, check with your insurance company.  Some will not cover it, as it is still considered experimental by some.  But, if it works, great.  Good luck.

 

cgm

 

Loopie4u2
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IRs

The 5mg and 10 mg oxymorphones are finally available again!!  Just saw the post.  I'm so happy although I must wait until I'm due for my script.  I had to switch to Roxycodone to replace oxymorphone 10irs.  The dr has been so mad about the opana situation that he gave me roxy 15mgs. He said" This is what you get for now.  I'm sick of this &??$!"  Nice, huh?  They do not work.  He should have at least given me the 30mgs.  It's not our fault that there has been shortages.  We (the patients) have been the ones suffering.  I'd like a bit more sympathy from my dr.  Anyway, I'm glad I can once again get some pain relief with the irs.  

http://www.fda.gov/Drugs/DrugSafety/DrugShortages/ucm050792.htm


That's the FDA website that has the info!Laughing

Sprinks
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I am certainly shaking my

I am certainly shaking my fist at Endo Pharmaceuticals. I mean the pharmaceutical companies just don't learn their lesson. I'd like to know how much money Purdue lost when they switch Oxycontin formulation. If it's not broken..don't fix it! I was such a huge fan of Opana ER when I first started taking it three years ago. I was on 30mgs TID up until April. I lasted not two weeks on the new stuff. I was lucky in the fact that the new Opana ER's didn't make me sick to my stomach like a lot of people complained of..I just found that the new 30mg tabs were equal to taking the 15mg old tabs..it seriously felt like I was only getting half of the medication. It did keep the withdrawals at bay..but my breakthrough pain skyrocketed. The biggest slap of all is that Opana ER is so darn expensive and it only works half as good..so I should only have to pay half the price. It was 100 dollars for 90 of the 30mg tabs. Ridiculous. I had no problem paying that much for the old stuff because it worked so well and the side effects were NIL. It also was worth the hunt..no chain pharmacies carry it and only a couple mom and pop pharmacies carry it. Most of the time they are out of stock and have to order it. But it was worth the waiting and worth the 30 minute drive because I knew I was getting a quality product.

After 9 days on the new formulation of the Opana ER I ran back to my doctor. He switched me over to 100mgs of MS Contin TID with 30mgs of Oxycodone every four hours. At last things have gone back to "normal." I wrote and called ENDO pharmaceuticals. I am hoping for a long shot..but with all these complaints maybe their will be a one in a million shot that they will switch back to the old formula. I know they are going to lose money. Opana ER wasn't really too popular to begin with anyway. Okay..END RANT.

celticgreenman
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Reformulation

Sprinks,

It is good that you notified the company of your reaction to the medication.  They need the "numbers" to show the FDA that patients are having problems with a medication.

As to the company "fixing something that wasn't broke", it was not their idea.  Companies do not want to have to "retool" a medication, if they do not have to.  The pharmaceutical companies have been told by the FDA/DEA that they have to change the formulation of the "abuse prone" medication to an abuse resistant form.  If they do not comply with the "request", they can see their medication removed from the market, resulting in a huge loss of revenue.

Agian, a company does not want to have to lay out very large amount of R and D money to change a medication that was working, and was not "broken".  They have been forced to do so.  And, it is not just in the USA that this is occuring.  Purdue had to change the formulation of OxyContin in Canada also.  The new formulation, which is the  same as the OxyContin OP, is called OxyNeo.  So, it is not just our FDA/DEA that is getting on the companies backs.

But, again, is is good that the company can get a feeling of how  many patients are having problems with the new formulation.  And the only way they can find out, is if patients file ADRs or write the company.

Hope you are doing well on your current regimen.

cgm

 

Sprinks
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Celticgreenman..you are

Celticgreenman..you are absolutely right...while the company is directly fixing what isn't broken...it wasn't their idea. It's the DEA/FDA that thinks that this is all such a great idea. Unfortunately Endo is going to lose a lot of money. I used to pay 100 dollars a month for my prescriptions! So people weren't on the Opana ER to begin with because it simply cost too much money. Now take the few people that actually were on the Opana ER(like I said I had no problem shelling out over a grand a year on the medication because in my opinion I was getting what I paid for). That was just for the Opana ER...that's not including the Lyrica(another pricey med due to only having the name brand available), ambien, oxycodone and klonopin I was taking. Endo just better be prepared they are in for a rude awakening. I also think it's a load of garbage that pain patients have to be punished because a few skells liked to abuse the medication. Addicts are always going to find a way to get what they want...the DEA isn't doing anyone any favors. I would have no problem taking the medication either...if it came in a 60mg strength(because the 30mg strength is equal to 15mgs...thus 60mgs would be equal to 30mgs...the strength that has served me well for so many years).

As for my current regimen...the MS Contin is getting the job done. It's not as good as the Opana ER...but it is MUCH easier to get(I can go to any pharmacy and get it within 20 minutes of dropping off my script as opposed to driving 45 minutes and waiting two days at the mom and pop pharmacy like I had to with the Opana) and it's also MUCH cheaper than the Opana ER because the MS Contin comes in generic brands.

Celticgreenman...thanks for the information as usual. You are always making valid points.

Cartier.PA-C
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I have a little bit of a

I have a little bit of a different view.  Sure the FDA/DEA has some major culpability to the change in formulation but don't underestimate the value of Endo and Perdue extending their patent protection for another seven or so years.  It's pretty extraordinary that the studies for the OP version were ongoing while the attorneys were fighting the generic Oxycontin release. And were quite successful. 

Opana ER is due in generic form within the year, lets wee what happens.  I think it will prove very interesting because it's not not the drug that is under patent protection it's the delivery method.  A generic company could, I think, make what amounts to the old formulation and have their product classified as "AB" because it matches the old version charicteristics.  Any patent lawyers on here?

Sprinks
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Cartier I was actually

Cartier I was actually wondering the same exact thing. If say a company picks up the generic formulation of oxycontin or Opana ER could they make it like the old formulations? Is it the actual drug company that it forced to make it tamper proof or is it the actual medication that no matter what brand it is that has to be made tamper proof. One can hope that it's the former and not the latter(though I am sure it's a long shot).