If you visit the aversion technologies website there are 2 formulations...one has niacin, one does not. I apologize for the confusion my post may have caused.
Personally, I'm all for the addition of a gelling agent. IR oxycodone has been the downfall of many of my friends and acquaintances. Since they seem to prefer manners of ingestion other than oral, this gelling abuse deterrent could be the wake up call they need...
My concern is the side effects. I have other health issues, and pain is only a symptom that is treatable to some extent, but I don't want to have to worry about controlling my GI problems or having them worsen because my medication changes. I take my medication as prescribed so that isn't a problem (now), but I am allowed to take an extra half pill awhile later or in between doses on my bad days. My Dr and I discussed pain increase and tolerance at my last visit and it was me who said that I didn't want to increase the strength of my medication thirty days a month when my pain is worse about 5-7 days a month, because I worry about tolerance. It was with the help and reading here at Pharmer of the trials and tribulations of others experiences that helped me understand and to learn and grow from understanding the whole concept of that, that has been a huge part in me being able to keep that under control.
Medications, alcohol, or food, whatever the persons crutch may be though is a personal choice. I have never believed that it was the foods fault, the alcohols or the medicines fault, when a person overindulges the blame is with them. We have debated this issue before.
http://www.knoxnews.com/news/2011/jun/21/062111bizbrfs/ It specifically states that the Oxecta will contain niacin. I just really don't like the idea of puting this stuff into my body. How do you guys feel about it?
This website was posted by medic008.
If you click of the "Physician Prescribing Information", you can get the package insert. Read it for yourself. No where in the package insert does it say that Oxecta contains niacin.
I am going to try to call Pfizer and ask about the niacin question. I'll give it a try on Saturday, but I may have to wait till Monday. Has anybody called Pfizer already?
No, I haven't called...but I'm interested in what they'll say. Thanks to everyone for posting about this. I have fears of being allergic to the new fillers. We'll see. I have to say, I do wish that they would just keep the Oxy IR the same. I'm tired of always worrying about things like this.
I personally didn't call, but a PA from another forum that I frequent did. Phizer confirmed it does not contain niacin. I am on my now, but I can link the discussion there when I have a chance.
It seems the FDA rejected the Remoxy formulation even though they approved the Oxecta. I was just looking through the feeds here and came across the article. http://www.reuters.com/article/2011/06/24/us-paintherapeutics-idUSTRE75N6P820110624
The last couple of lines in the Reuter's article state:
"Last year, Acura had also faced regulatory roadblocks when its marketing application for Acurox -- an earlier version of Oxecta.
The company then filed a fresh marketing application, which did not contain the additional benefit of preventing oral abuse, but eventually got the FDA's nod."
Niacin had been added as a deterrent to oral abuse, i.e. if one takes more than prescribed, it results in too much of the niacin, cauing the itching and flushing.
Pfizer is not open for information calls on the weekend. So, I will try early Monday morning.
If one takes more than prescribed? But some people are Rx'ed higher doses than others, is the niacin higher in the 30mg pill than it is in a 15mg pill, or does a person build tolerance to niacin as well....... haha
The amount of the niacin would be the same in each of the tablets, no matter what the milligrams of the oxycodone. Thus, you would not be able to do, what can be currently done, with the plain IR oxycodone; such as, is you needed 60 mg of oxycodone, currently you could conceivable take 12 5mg tablets, rather than a 60mg one (this is just an example of math, I don't know if a 60mg tab is made, that's not the point). But, if it was with the niacin added, the 12 5mg tabs would cause you to have too much niacin. Taking one extra tablet would most likely not cause any problems. The idea was to keep people from taking handfuls of tablets, which some abusers do.
Anyways, it sounds like it is a moot point at present, because this medicine did not get approval.