Oxycodone on a full stomach

18 replies [Last post]
frankwhite
User offline. Last seen 7 years 36 weeks ago. Offline
Member
Joined: Mar 14 2010
Posts: 2

Hello everyone, I've been a lurker on these boards for quite a while but this is my first time posting. I have a question about efficacy of oxycodone on a full or empty stomach. I've been having treatments on my back for quite a while now and I've been taking some far more powerful oxys.  I want to make sure I get the maximum effectiveness out of them so I'm not wasting them or running out of them by taking more.

 

So, in it's simplest form, my question is does having a meal effect how effective or strong oxys feel?

 

This may be a completely idiotic question, if so, I apologize in adance.

 

Thanks,

jp

Flyer1976
Flyer1976's picture
User offline. Last seen 7 years 15 weeks ago. Offline
Member
Joined: Mar 24 2008
Posts: 542
Its a good one

Frank White!! HAHAHAH!! Nice name!!! :-) I am keeping you up on the active forum.

jdschmidt
jdschmidt's picture
User offline. Last seen 6 years 33 weeks ago. Offline
Member
Joined: Dec 1 2009
Posts: 366
Yes it does. Taking it with

Yes it does. Taking it with food will decrease it's effectiveness. Should say that in the prescription leaflet.

 

 

 

 

edit/g

Ivy
User offline. Last seen 3 years 10 weeks ago. Offline
Member
Joined: Feb 18 2010
Posts: 1976
People assume too

People assume too much.Yeah,there are many drug seekers and people who take pain medications without a prescription..but someone who has only one post with one legitamit question deserves the benefit of the doubt.

Don't we,or wouldn't we get a little perturbed if a Dr didn't give us that same benefit.Think of where you would be sitting in CP without it.

WOODSTOCK
WOODSTOCK's picture
User offline. Last seen 5 years 16 weeks ago. Offline
Member
Joined: May 28 2009
Posts: 1620
I

HEARD ANY MEDICATION will be its strongest if taken with a pint of pure virgin olive oil, I don t know about them urban or old world legends.

Woodstock

NOT NOT NOT NOT NOT NOT NOT NOT NOT

kelly690
kelly690's picture
User offline. Last seen 4 years 20 weeks ago. Offline
Member
Joined: Feb 22 2009
Posts: 509
I've actually read that

I've actually read that taking Oxycodone after eating a high fat meal causes the greatest plasma concentration, and that is why doctors often will tell patients NOT to take their meds after a high fat meal. My doctor told me to take my meds after eating because there is less of a chance of nausea and that if I take it on an empty stomach it will go through my body quicker. That makes sense, I mean, if you take it with food them it will be in you longer because it will mix with the contents of your stomach. If you take it on an empty stomach then it will go right through you. Here is what I found on drugs.com:

 

One OxyContin 160 mg tablet is comparable to two 80 mg tablets when taken on an empty stomach. With a high-fat meal, however, there is a 25% greater peak plasma concentration following one 160 mg tablet. Dietary caution should be taken when patients are initially titrated to 160 mg tablets (see DOSAGE AND ADMINISTRATION).

SoloCPhT
User offline. Last seen 6 years 5 weeks ago. Offline
Member
Joined: Oct 6 2005
Posts: 2231
 Taking OxyContin with a high

 Taking OxyContin with a high fat meal will increase its peak plasma level  but it will take a lot longer to kick in than when taken without food. Ive actually noticed that taking immediate release oxycodone with high fat/sugar foods like snack cakes, seems to make them feel stronger but also like mentioned before take longer to kick in. Other pain meds like hydrocodone/apap or codeine/apap IMHO dont seem to be effected the same way, in my experience taking them with food or milk makes them work barely at all which is kinda weird since I can take Oxycodone with milk and it has no effect on it.

Sprinks
Sprinks's picture
User offline. Last seen 4 years 9 weeks ago. Offline
Member
Joined: Jan 15 2010
Posts: 1187
I notice if I take my

I notice if I take my immediate release meds with food they do seem take longer to kick in and work(I take Dilaudid BTW). With my Opana ER if I take it with a meal it risks all the medicine being released at one time which is dangerous...which is why they say to take it a couple hours before or after eating. Not sure if oxy is the same as I have never taken it.

Deanna
Deanna's picture
User offline. Last seen 6 years 46 weeks ago. Offline
Member
Joined: Nov 15 2008
Posts: 135
opana and food

 I never knew that if you took Opana with food, all the medicine would be released all at once! I tried finding more info on this but came up with nothing. Sprinks, could you pm me with the information please.

 Thanks, Deanna

frankwhite
User offline. Last seen 7 years 36 weeks ago. Offline
Member
Joined: Mar 14 2010
Posts: 2
Thank you

Thank you all for all of your feedback. That's exactly the sort of information I was looking for. I didn't see who said it (maybe the post was deleted) but I am not a drug seeker or abuser. I have regular treatmennts and a pain management dr that prescribes all of my meds. I appreciate you all taking the time to educate me on this. Thanks again.

dc.gg
User offline. Last seen 7 years 22 weeks ago. Offline
Member
Joined: Apr 21 2010
Posts: 36
I've found that it works in

I've found that it works in two different ways. If your goal is quick pain relief and you don't mind maximizing the euphoria that sets in about 20-30 minutes after administration, then go the empty stomach route. But if you're looking for longer-term pain relief, take it with fatty foods. What I normally do with my chronic migraines is take my first day's dose on an empty stomach. That kills the pain quickly. Then, throughout the day, I take the rest with food or at least a snack. People who take Oxy to achieve that "high" will suggest taking it on empty, but for me this causes some Dig/GI discomfort. So there are benefits in both means. If I get a sudden, acute attack, I will take 20mg on empty, but if the meds wear off, I'll eat something and then take more to sustain the pain relief.

Of course, this applies to Percocet. I have no idea how this would work with Oxycontin. Taking it on empty, you will notice the euphoria and energy more. But it won't last as long. Taking it on full, and the euphoria is dulled/blunted, but the pain relief lasts longer.