klonopin (high dose regimen)

20 replies [Last post]
Dr. Lois
User offline. Last seen 6 years 51 weeks ago. Offline
Member
Joined: Apr 12 2007
Posts:
The short answer is that a

The short answer is that a chemical in grapefruit juice inhibits the enzyme that breaks down many drugs, including benzodiazapines. 

KnightMetal
User offline. Last seen 10 years 30 weeks ago. Offline
Joined: Jun 5 2006
Posts:
So does this make the drug

So does this make the drug stronger or weaker?

Or doesnt matter, has no real effect on the actual drug.

Well I found the answer to my question, it seems tho it takes the drug to very high levels in the body.

For example, as much as 99% of BuSpar (Buspirone) is normally metabolized before the drug ever enters the bloodstream. When taken in the presence of grapefruit juice (not even at the same time), the amount of BuSpar in the system could increase as much as 400% - a hazardous situation.

 

Read more here and here

KnightMetal
User offline. Last seen 10 years 30 weeks ago. Offline
Joined: Jun 5 2006
Posts:
what about

What about vicodin and grapefruit juice?

 

 

 

Dr. Knight uses

Makaveli
User offline. Last seen 10 years 23 weeks ago. Offline
Member
Joined: Sep 10 2007
Posts:
I agree

Nobody should be able to tell another person what they do or dont need to feel right

-Makaveli

otto
User offline. Last seen 5 years 50 weeks ago. Offline
Member
Joined: Jun 3 2012
Posts:
agreement

Bad, suspicious, judgemental pharmacists stink. I had one at Walmart I ditched for Walgreens. I had an extra Tyl3 script due to dental work in addition to the 4/day I take for digestion. She acted like I was doctor shopping, didn't bother to call my doctor or dentist like a responsible pharmacist that is concerned about possible addiction or fraud. I reported her--she still works there but I had the satisfaction of telling her she was discriminating gainst me and was judging me unfairly and reported her to her regional manager and Pharm board. If you're dealing with a &!?!*@@ I'd complain up the ladder and find a new pharmacist.

Otto

 

gm2 LirtoviR
User offline. Last seen 34 weeks 17 hours ago. Offline
Member
Joined: Apr 13 2009
Posts:
When I was...

prescribed clonazepam, I was Rx'd 2mg BID.  4mg a day.  I think the OP's doctor maybe could have written it out as 1-2  tabs BID not to exceed 4mg in the day.  Clonazepam is potent and is long acting.  The pharmicist had probably never seen that medication Rx'd that many times in a day for anxiety.  I think I've heard of Rx's for TID but not QID.  Plus he might not have known tolarences for the OP.  As far as the police getting involved I probably would have had a fit and complained up the pharmacy latter especially for the embarresment (IMHO) I would have felt.

penny for thoughts

louis76
User offline. Last seen 3 years 2 weeks ago. Offline
Member
Joined: Dec 1 2009
Posts:
Really?

My mom is prescribed 1mg Klonopin 4x daily also and has 1mg xanax for anxiety attacks? This dose is considered average where i come from. have a great day.

mel1979
User offline. Last seen 5 years 19 weeks ago. Offline
Member
Joined: Apr 17 2012
Posts:
klonopin

 I am prescribed 2mg 3x a day so i do not think you are being over prescribed.

celticgreenman
celticgreenman's picture
User offline. Last seen 4 years 7 weeks ago. Offline
Member
Joined: Nov 10 2010
Posts:
dose

The dosage of clonazepam (Klonopin) is variable, by case, and reason for taking it.  The following shows that it should be started low, but with continued usage, the dose will usually have to be increased.

From Medicine.net:

The dose of clonazepam is tailored to the patient's needs. For seizures iin adults the initial dose is 1.5 mg daily in 3 divided doses. Dosage may be increased by 0.5 to 1 mg daily every 3 days until seizures are controlled or side effects preclude further increases in dose. The maximum dose is 20 mg daily. The initial dose for panic disorders is 0.25 mg twice daily. The dose may be increased to the target dose of 1 mg daily after 3 days

cgm

.

slosippa
slosippa's picture
User offline. Last seen 2 years 21 weeks ago. Offline
Member
Joined: Aug 10 2010
Posts:
klonopin dose

a relative of mine is Rx'd 60 2mg klonopin which is equivelant to the OP dosage......IIMHO this is NOT  a high dose at all...the POLICE coming to the pharmacy and harrasing you???? are you kidding??? i would have been been LIVID! if the Rx was legitimate,not only would i have immediately changed pharmacies,i would have bad mouthed that other pharmacy to your doctor,patients...heck,i might would have even looked into an attorney for deflaming your character like that! lol