Which Fentanyl patch manufacturer is best?

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goat
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Mylan

I am still using mylan brand as others seem to break me out in a rash or the reservoir types don't stick and are so big they come off easy.

gaucho
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Fentanyl Patch - best manufacturer?

I will agree that the reservoir patches by Mylan USA are very good indeed - in my view the ONLY really decent drug made by that company, not to be confused with the Mylan tablets which used to be Merck Generics, which are all vastly superior to any Mylan USA tablets.

However, have you ever considered the DOLFORIN patches made by Gedeon Richter, the oldest still-operating pharmaceutical company in Hungary, who now also have a factory next door in Romania?

Those (reservoir only, do not use the matrix patches!) are about the finest I have ever tried.

IN terms of matrix patches, Durogesic D-Trans remain the 'gold standard', but Actavis MATRIFEN, which may or may not be available in the USA, I dunno, are quite good also. Sandoz patches were disappointing and I required a 100mcg/hr patch rather than my usual 75mcg/hr.

edited G.

goat
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mylan

 "I will agree that the reservoir patches by Mylan USA are very good indeed"  ??

   I have been using Mylan brand for about 5 years and during that time they have been the matrix type.



joelt2105
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I have been on  Fentanyl, a

I have been on  Fentanyl, a God send, in my situation and am using the Actavis resorvoir patch after using the Mallinckrodt patch I found the Actavis are way better.  If I didn't now have access to this amazing pain killer, I would be wheel chair bound but Actavis has been a great help.  I rarely use the BK pain meds.  As for the danger and risk of death, yes I understand it..  What most people do not understand, being street junkies or suburban junkes is that the bioavailability is equal to the sublingual preperation.   You have to remember that ONE patch must have enough pain medication for at least THREE days!  I read a report by JAMA, in which ER doctors were discussing the deaths by kids using fentanyl.  What you have to understand is that  a 25 mch release patch has a total of 2.5 miligrams of fentanyl.  The drug is so potent (100 times the potency of morphine and 50 times more potent than pharmaceutical grade [filtered word]!)  When you decide to abuse the patch, you really need to understand that you are realising 2.5 milligrams of the most potent synthetic opioid in one sitting and that will  kill you, if you do not already have a HIGH tolerance to opiods.  I mean, when they measure this drug they use MICROGRAMS as opposed to the usual, say, 25 milligrams of morphine. Milligrams are one thousandth of a gram. whereas MICROgrams are one MILLIONTH  of a gram.  If you are getting the patches for legitimate reasons, just take them as directed.  If you are wanting to use it recreationaly and have mid tolerance to opioids, you run the real risk of dying.   I remember reading that even after the 72 hours have passed and time to use a new patch, the old patch has an average of 40 percent of the med still inside it!  Just don't do it.  The difference between getting "high" on Fentanyl and the very real risk of dying is the difference between a grain of sand. 

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goat
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re:

  In this intense florida heat i have had 2 patches fall off on the first day of application this month and 1 or 2 fell off on day 2.  sunday night the last patch had hit the 72 hour mark and withdrawls started.  i have been taking 8-9 oxy 15 a day to try to keep the edge off and its not even close.  Fent is nothing to play around with.  fingers are crossed that the pharmacy will have my meds this afternoon.  its been brutal.

goat
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re:

  pharmacy didnt have any brand of patches in my strength...I did get my oxycodone which i am taking 2 at a time until i feel normal and hope i hear something tomorrow...was supposed to go  primitive camping thursday thru tuesday.. reservations already made....blahhhh

gaucho
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Fentanyl patches: gel reservoir vastly superior to matrix

In my opinion, US Mylan gels, Teva and Gedeon Richter's DOLFORIN brand.

Personally I prefer the IR intranasal aqueous sprays available from 50 to 250mcg per spray as it works within a minute or so for acute pain; duration of action is up to 2.5 hours so is perfect as rescue analgesia.

I find the highest dose patch, 100mcg/hr over 72 hrs, to be insufficient for my pain levels which require the 120mg strength 0xyC0ntin, which unfortunately has an average duration before further analgesic is needed of 6.5 hrs and certainly nothing close to the 12 hrs claimed on the box. (The pseudo-0C tablets (0P) now dispensed in the US, which I have tried, seem half strength and give awful gastric side effects, which explains why so many have switched to IR and sourcing from UK/EU to avoid US pills, since real ones were banned there 6 yrs or thereabouts ago.

But those gel patches are definitely the most effective. Durogesic and Matrifen feel much less effective. Nasal spray has much higher bioavailability and a very rapid onset, making those my #1 fentanyl choice.

goat
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and...............

 I am in the same situation again.  patches will not stay on as I have went back to work in the florida sun.
 dr said lets try oxycontin and against my better judgement tried them.
 i cant believe how bad my gut felt.  so i am back on the patch trying different brands.  malinckrodt are stiff and rarely stick for 2 days.  
  I have tried the askina overlays with the mylan brand but the overlay often will pull the patch off.

  fent has helped me get back to work and has the least side effects.  I am going to try duragesic brand name next month